Description

Multilevel latent class analysis (MLCA) was developed more than a decade ago to address nested data, such as individuals nested within a higher-order structure (e.g., students nested in classrooms). By applying MLCA to the analysis of intensive longitudinal data (ILD), we can better understand the heterogeneity of behavior patterns in daily life and identify within-person vs. between-person risk factors. Specifically, we can model comprehensive, within-day substance use patterns, incorporate day-level psychosocial and person-level predictors of patterns, and predict acute (e.g., next-day) outcomes.

Modeling Latent Class Variables in the Context of Intensive Longitudinal Data (ILD)

Marginal Modeling Approach to MLCA

Two-Level Modeling Approach to MLCA
with latent classes at both levels

Marginal models (e.g.., generalized estimating equations applies to longitudinal data), are a popular alternative to random effects models for repeated-measures data. Marginal models estimate average effects in a population and produce cluster-adjusted, robust standard errors; this can be an attractive alternative to random effects models when estimating complex latent variable models.

Software resources

This approach to random effects modeling employs latent class variables at the day-level and person-level. The person-level classes summarize the random effects of interest and reflect heterogeneity across persons in their probabilities of having certain types of days. In some of the literature, this is referred to as the “non-parametric” approach to MLCA. This approach to MLCA is emerging as particularly useful in empirical data.

Software resources

Advanced Models: MLCA

MLCA: Marginal approach with covariates at day-level and person-level

Description

This model estimates six day-level latent classes of substance use consequences using a marginal modeling approach to account for the nested data structure. One one day-level covariate (daily positive affect) and person-level covariate (student is under legal drinking age) are included to predict consequence latent class membership.

Software Downloads

Mplus

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MLCA: Marginal approach without covariates

Description

This model estimates six day-level latent classes of substance use consequences using a marginal modeling approach to account for the nested data structure.

Software Downloads

Mplus

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MLCA: Non-parametric approach with covariates at the day-level and person-level

Description

This code fits a 2-level latent-class model with covariates using a “non-parametric approach.” This model simultaneously estimates day-level classes of substance-related consequences and person-level classes that group individuals based on proportion of each type of day. This model includes covariates at each level to estimate associations with both the day-level and person-level classes.

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R

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MLCA: Non-parametric approach without covariates

Description

This code fits a 2-level latent-class model without covariates using a “non-parametric approach.” This model simultaneously estimates day-level classes of substance-related consequences and person-level classes that group individuals based on proportion of each type of day.

Software Downloads

R

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